For instance, Ongur et al.42 showed that a specific haplotype of four SNPs within GLS1, the gene encoding for the enzyme glutaminase generating glutamate from glutamine, was significantly associated with glutamine/glutamate in the parietooccipital cortex and rs956572 in a mixed group of healthy controls and patients with bipolar disorder and schizophrenia42. The gene discussed is GLS; the disease is bipolar disorder.