After adjustment for the history of diabetes, FPG and HbA1c, hs-CRP (OR=1.268, 95%CI 1.013–1.588), Crouse score (OR=1.863, 95%CI 1.053–3.297) and 5-hmC (OR=1.767, 95%CI 1.250–2.499) were significantly associated with coronary atherosclerosis, while there was no significant association between 5-mC level and coronary atherosclerosis. Here, CRP is linked to coronary atherosclerosis.