In this study, 5 agammaglobulinemia patients received between 1000 and 2000 mL plasma over a period of 1 to 3 days, which led to an increase in serum IgA to 1500 mg/L and saliva IgA levels to 1 mg/L in one of these patient, much lower compared to saliva of healthy individuals (120–200 mg/L) [19]. The gene discussed is CD79A; the disease is agammaglobulinemia.