In our study, the only exception was Splenomegaly (P = 0.021) with CD38 expression and no significant correlations of ZAP-70 and CD38 expressions with age, sex, hematological parameters and clinical findings at presentation were found (Additional file 1: Table S1–S3), which was inconsistent with Abdelgader et al. [24], Gogia et al. [29], Waheed et al. [28]. Here, CD38 is linked to Splenomegaly.