CTNNB1 and cancer: The most highly implicated IPA network was “DNA Replication, Recombination and Repair, Cell Morphology, and Cancer, Hematological Disease, Immunological Disease.” We merged the total 5 networks related to the cell cycle and immune response pathways and found that IFNG (IFN-γ) and CTNNB1 (β-catenin) were in the core modules within the whole network (Additional file 2: Fig. S1a).