To determine whether elevating RUNX3 by miR-301a deletion alters lung tumor cell phenotype, we first measured the expression of miR-301a and RUNX3 in noncancerous lung epithelial cell line 16HBE and NSCLC cell lines PC9, H1975, A549 and H1299. The gene discussed is RUNX3; the disease is non-small cell lung carcinoma.