These results suggest that FASN could be a key regulator of migration and invasion in NSCLC cells, but it is not ubiquitous in all NSCLC cells since A549 was isolated from primary lung cancer while NCI-H1299 was isolated from metastatic lung cancer (lymph node) and contained the NRAS gene mutant. The gene discussed is NRAS; the disease is non-small cell lung carcinoma.