RIPK3 and cervical carcinoma: Schmidt et al. [92] showed that necroptotic cervical cancer cells induced by PolyI:C, which is a viral dsRNA analog that triggers necroptosis in cervical cancer cells, produced interleukin-1α (IL-1α), which is essential for the activation of DCs to release IL-12, which is a cytokine pivotal for antitumor effects, and that the expression level of RIPK3 in cervical carcinoma cells may predict the efficacy of PolyI:C-induced immunotherapy; therefore, immunotherapeutic treatment should be customized according to the RIPK3 level.