Thus, according to TBEVHostDB, only TLR3 and ARID1B have known SNPs (rs3775291 for TLR3 and rs287886 for ARID1B) associated with disease severity in adults from the Lithuanian population and in Russian individuals from Novosibirsk [38, 44] or with IL-10 concentration in cerebrospinal fluid of the Polish patients with TBE [45] respectively. Here, IL10 is linked to tick-borne encephalitis.