Among these, actin (cytoplasmic1), fibronectin, vitamin D binding protein (DBP), coagulation factor XIII A chain, fibrinogen alpha chain, and complement factor H-related protein 1 were increased and complement C3, adiponectin, and prothrombin were decreased in AIS patients with Lenke type 5 curvature compared to controls. The gene discussed is F2; the disease is androgen insensitivity syndrome.