VIM and head and neck squamous cell carcinoma: Finally, another study by Puram et al. showed that the head and neck squamous cell carcinoma (HNSCC) cells from patients exhibit a hybrid E/M phenotype characterized by co-expression of epithelial markers such as EPCAM and KRT17 and mesenchymal markers such as vimentin and TGF-β-induced (TGFBI) through single-cell transcriptomic analysis [76].