For example, though both invasive ductal carcinoma (IDC) and invasive lobular carcinoma (ILC) exhibit collective invasion patterns, the collective invasion in IDC lesions maintains intercellular E-cadherin while collective invasion in ILC lesions loses intercellular E-cadherin but retains CD44 for intercellular junctions [129]. This evidence concerns the gene CDH1 and invasive ductal breast carcinoma.