The transfection of VECAD-HO-1 further increased the numbers of adipocytes of small cell size as measured by lipid droplet size (p < 0.05), decreased adipokines, TNF, ICAM, VCAM and improved vascular relaxation to acetylcholine similar to HF mice administered CoPP in a more specific and sustained fashion (Figure 2, Figure 4 and Figure 5). The gene discussed is TNF; the disease is hydrops fetalis.