GLI1 and persistent truncus arteriosus: However, a larger range of OFT defects was observed in Gli1-CreERT2/+; Gata4fl/+; Smofl/+ embryos, including DORV (3 out of 5, Fig 4C and 4C’), OA (1 out of 5, Fig 4D and 4D’) and persistent truncus arteriosus (PTA) (1 out of 5, Fig 4E and 4E’).