Numerous studies have confirmed the engagement of VGCCs in age‐related disease, including Parkinson disease (Cav1.3) (Zamponi et al., 2015), ataxia (Cav2.1) (Dorgans et al., 2017), Alzheimer's disease (Cav3.1) (Rice et al., 2014). The gene discussed is CACNA1A; the disease is Alzheimer disease.