RUNX1T1 and acute myeloid leukemia: AML1‐ETO triggers the silencing of miR‐193a and in contrast, miR‐193a decreases AML1‐ETO expression via targeting its binding sites, suggesting that a feedback circuitry is formed in AML cells bearing AML1‐ETO.32 It is possible that MLT‐induced degradation of AML1‐ETO disrupts the feedback circuitry and increases the expression of miR‐193a.