In the current study, JQ1(+) treatment of non-ILD lung fibroblasts led to an increasing trend in Antioxidant Response Element (ARE) promoter-driven gene transcription (Figure 5(a)) and a statistically significant increase in NRF2 mRNA both in absence and presence of TGF-β (Figure 5(b)), while JQ1(-) had no effect. This evidence concerns the gene NFE2L2 and interstitial lung disease.