For instance, C57Bl/6 MyD88-null mice are more susceptible to infection with L. major than wild type animals (de Veer et al., 2003) while C57BL/6J TLR2−/− mice infected with L. braziliensis are more resistant to infection than C57BL/6J wild type mice (Vargas-Inchaustegui et al., 2009). Here, MYD88 is linked to infection.