Although IL-10 is associated with parasite persistence and dissemination (Bomfim et al., 1996; Anderson et al., 2008), it is also important for controlling the exaggerated inflammatory response associated with pathology observed in parasitic diseases such as malaria, Chagas disease, and leishmaniasis (Li et al., 2003; Costa et al., 2009, 2015; Gautam et al., 2011). The gene discussed is IL10; the disease is leishmaniasis.