As defined by Wallace et al. (2011), the criteria for an inactive disease are: no joints with active arthritis; no fever, rash, serositis, splenomegaly, or generalized lymphadenopathy attributable to JIA; no active uveitis; C-reactive protein (CRP) or erythrocyte sedimentation rate (ESR) level within normal limits; duration of morning stiffness less than 15 min; and a physician’s global assessment of disease activity score of best possible on the scale used. The gene discussed is CRP; the disease is arthritic joint disease.