A cystic kidney disease panel should include adequate coverage of PKD1, PKD2, PKHD1, Daz-interacting zinc-finger protein 1-like (DZIP1L), HNF1B and genes for other ciliopathies such as nephronophthisis (NPHP) and Bardet–Biedl syndrome (BBS). This evidence concerns the gene PKD1 and Bardet-Biedl syndrome.