We noted that patients with higher levels of baseline HbA1c, older adults, obesity participants, active smokers, patients without exercise, patients with comorbidities, patients with more than one OHA, patients receiving insulin treatment, patients from lower tier hospitals, were less likely to achieve the glycemic control, blood pressure control, lipid control in Chinese patients with newly diagnosed type 2 diabetes based on this study. This evidence concerns the gene INS and obesity due to melanocortin 4 receptor deficiency.