CD19 and B-cell chronic lymphocytic leukemia: In order to characterize CLL chromatin modifications in correlation with transcriptional activity, we analyzed the chromatin landscape and the transcriptome of CD19+ B cells from peripheral blood from 23 CLL patients and from 17 pools of non‐malignant B cells (NBCs) of healthy donors (Figs 1 and EV1, Appendix Fig S1 and Table S1, [Link], [Link]).