Flow cytometric analysis revealed that upregulation of GPAA1 profoundly suppressed but knockdown of GPAA1 increased the proportion of cells in the G0/G1 phase, indicating that GPAA1 may stimulate the G1-to-S phase transition in stomach cancer cell (Fig. 2f,and Additional file 2: Figure S2). This evidence concerns the gene GPAA1 and gastric cancer.