Among these, we identified six miRNAs (miR-95-5p, miR-4512, miR-877-3p, miR-1273d and miR-5585-3p) with inverse expression patterns to four prominent genes (CSF3R, CXCL1, CXCL3, and IL1B) within key impaired immune pathways identified due to CF (Fig. 8 c). The gene discussed is CXCL3; the disease is cystic fibrosis.