The pathways influenced by CF included agranulocyte/granulocyte adhesion and diapedesis, differential regulation of cytokine production in macrophages and T helper cells by IL-17A and IL-17F, and role of IL-17F in allergic inflammatory airway diseases, while the immune pathways influenced by CF phenotype were natural killer cell signaling, FC Epsilon R1 signaling, PI3K signaling in B lymphocytes, and Th2 pathway. Here, IL17F is linked to cystic fibrosis.