For example, six miRNAs (miR-1972, miR-1273 h-5p, miR-4512, miR-877-3p, miR-1273d, and miR-5585-3p) showed inverse expression correlation with four immunity-related target genes (CSF3R, CXCL1, CXCL3, and IL1B), which are prominent in dysregulated immune pathways associated with CF (Fig. 8 c). This evidence concerns the gene IL1B and cystic fibrosis.