EPS8 was overexpressed in all six breast cancer and NSCLC cell lines (MDA-MB-468, H460, A549, H1975, MCF-7 and BT549), moderate expressed in normal cell lines (MCF-10A and BEAS-2B) and very low expressed in IM-9 cell line (Fig. 2a). The gene discussed is EPS8; the disease is breast carcinoma.