Moreover, EE02 did not result in a significant promotion of apoptosis in normal cell lines (MCF-10A and BEAS-2B, less than 7% apoptotic cells) and PBMCs from 5 untreated healthy volunteers (less than 5% apoptotic cells), suggesting that EE02 possesses specificity toward cancer cells that overexpress EGFR and EPS8 (Fig. 3b and c). Here, EPS8 is linked to cancer.