KCNQ1 and Schnyder corneal dystrophy: These mutations include the rs199472830 (p.Phe29Leu) and rs199472882 (p.Pro297Ser) mutations of KCNH2, as well as the rs120074178 (p.Arg190Trp) mutation of KCNQ1. Besides, a study in the Finnish population reveals the occurrence of KCNH2 rs199472918 (p.Leu552Ser) and rs36210422 (p.Arg176Trp) mutations among three probable SCD cases, although statistical analysis suggested a lack of significant association between the mutations and SCD risk [31].