Interestingly, CGN and SCGN were both better individually than whole Kappaphycus, and this is evident in the smaller sizes of adipocytes in these two groups compared to group T. As adipocytes are central to obesity pathology, we measured two adipocytokines, leptin and adiponectin, levels in the mice. Here, LEP is linked to obesity due to melanocortin 4 receptor deficiency.