Moreover, ERKs mediate proliferation and/or migration in response to IL-8 in pancreatic [53] and cervical [54] cancer, to IL-34 in colon cancer cells [55], and to IL-13 in glioblastoma multiforme [56], working as downstream collectors of the pro-tumorigenic inputs of different cytokines. The gene discussed is IL34; the disease is malignant colon neoplasm.