The sedentary mice fed HFD with experimental colitis presented significantly higher colonic tissue content of TNF-α, IL 1β, IL-6, IL-17, INFγ, and IL-10 as compared with the respective values of these cytokines recorded in sedentary mice fed SD (p < 0.05) (Figure 5 D–I). The gene discussed is IL17A; the disease is colitis.