CXCL2 and melanoma: Many of the AR-bound, SLNCR-regulated genes are known or believed to play important roles in melanoma etiology, including the GRO oncogene and chemokine ligand CXCL2 (log2 fold change, −2.0), JUN oncogene (log2 fold change, 0.9), STAT3 transcription factor (log2 fold change, −0.9), interleukin-24 (IL-24; log2 fold change, 2.5), and melanoma cell adhesion molecule (MCAM; log2 fold change, 1.2).