Multiple EM for Motif Elicitation (MEME) and TOMTOM analysis (Bailey et al., 2009) identified enrichment of the DNA binding motif of REST (or NRSF), a transcriptional repressor that regulates AR activity in prostate cancer (p = 1e–191; Figure S6A; Svensson et al., 2014). Here, REST is linked to Familial prostate cancer.