However, the growth of S. aureus showed no difference between PGRP-SAseml and PGRP-SAseml; PGRP-LCΔE12 double mutants until 36 h post-infection, indicating that PGRP-SA was the main restricting factor for wild-type S. aureus, and loss of PGRP-LC only added to the phenotype at later stages of infection (Figure 6A). This evidence concerns the gene PGLYRP1 and infection.