FPR1/FPR2 expression ratio on neutrophil was significantly increased in the treatment-naive OSA (0.73±0.42) group as compared with that in the HS group (0.28±0.1 MFI; p = 0.001/adjusted p = 0.001) and that in the PS group (0.41±0.18 MFI; p<0.001/adjusted p = 0.013), and also increased in the severe OSA on CPAP group (0.56±0.23 MFI, p<0.001/adjusted p = 0.023) as compared with that in the HS group (Fig 2C). The gene discussed is FPR1; the disease is obstructive sleep apnea syndrome.