Curcumin (5–20 μmol/L) was also shown to concentration-dependently inhibit human lung adenocarcinoma cells (CL1–5) by invasion and metastasis via the upregulation of the DnaJ-like heat shock protein 40 (HLJ1) associated with tumour suppression, via activation of the JNK/JunD pathway [85]. The gene discussed is DNAJB4; the disease is lung adenocarcinoma.