The patch‐clamp analysis demonstrated that human adipose‐derived mesenchymal stem cells (AMSCs) possess functional VGCCs, although they account for <1%.48 However, analysis of cytoplasmic Ca2+ concentration evoked by ATP, high K+ solution, GABA and caffeine demonstrated that functional VGCCs are absent in AMSCs isolated from rats.49 The previous work on AMSCs from chronic kidney disease patients by Thi et al had indicated a possible association between Cav1.1 and defective proliferation of AMSCs. The gene discussed is CACNA1S; the disease is chronic kidney disease.