Inhibition of various tumor cell lines including promyelocytic/monocytic leukemia cells, colon cancer cells, and gastric adenocarcinoma cells Increase in insulin secretion Antihypertensive activity by inhibition of angiotensin I-converting enzyme and anti-inflammatory effect by blocking NF-κB pathway Counteractive effect on oxidative stress in neuronal cells. The gene discussed is ACE; the disease is malignant colon neoplasm.