CD8A and infection: However, contrarily to the negative effects described above for HSV over DCs, another study found that upon exposure to HSV-1, a human CD8α+ plasmacytoid DC subset increased the expression of markers associated with the migration of these cells to lymph nodes, and that these DCs were able to promote the activity and functions of T cells, B cells and NK cells, which were recruited to the infection site (Schuster et al., 2015).