Our results contrast with the findings of La Doucer et al. [18], who noted not only that canine well-differentiated liposarcomas express UCP1 but also that a number of such tumours express smooth muscle actin and desmin with one case expressing myogenin; in our experience, these antigens are rarely expressed in well-differentiated or other subtypes of liposarcoma. The gene discussed is DES; the disease is neoplasm.