KIR3DL1 and autoimmune hepatitis: Additionally, the low frequency of the inhibitory KIR/KIR-ligand combinations KIR3DL1/HLA-Bw4 and KIR2DL3/HLA-C1 coupled to the high frequency of the HLA-C2 high affinity ligands for KIR2DS1 may contribute to unwanted NK cell autoreactivity in AIH (74).