These diagnoses included polycystic liver disease (n = 5), epithelioid hemangioendothelioma (n = 3), acute liver failure (n = 3), hepatic adenoma (n = 2), cholangiocarcinoma (n = 2), Wilson's disease (n = 2), alpha-1 antitrypsin deficiency (n = 1), neuroendocrine carcinoma (n = 1), and Rendu-Osler disease (n = 1). This evidence concerns the gene SERPINA1 and acute liver failure.