When the MYC+N1ICD mice were injected with [U-13C]-glutamine, blood glutamine enrichment was not significantly different (Fig. S11a) but Krebs cycle intermediates in MYC+N1ICD tumours showed increased percentage of 13C enrichment, particularly for 13C5-citrate (Fig. 6g), reminiscent of the SCC tissue slices (Fig. 4b). Here, MYC is linked to neoplasm.