Reanalysing data from a rigorous study that performed immunohistochemistry on 49 NSCLC patients with an antibody against the Notch1 intracellular domain (N1ICD) and quantified scoring based on its expression in the nucleus46 revealed that N1ICD is associated with SCC (Fig. 5c). Here, NOTCH1 is linked to non-small cell lung carcinoma.