CD34 and thalassemia: To evaluate the therapeutic potential of the U7.BP + 623 snRNA lentiviral vector in the ultimate target cell, CD34 + haematopoietic progenitor cells derived from βIVS2-654-thalassaemia/HbE patient were transduced with U7.BP + 623 snRNA or the scrambled sequence of U7.BP + 623 (SCR) in a lentiviral vector.