The results from immunoblotting assays of LC3B and PARP-1 in both KSHV/EBV-positive and -negative tumor cells with or without nAg treatment, showed that LC3B-II accumulation and PARP-1 cleavage in the KSHV/EBV-infected tumor cells were consistently higher than that in the KSHV/EBV-uninfected tumor cells (Fig. 4a–c), indicating that nAg could induce stronger autophagy and apoptosis in KSHV/EBV-latently infected tumor cells. The gene discussed is PARP1; the disease is neoplasm.