NPTX1 and neoplasm: Statistical analysis revealed that low NPTX1 expression strongly correlated with tumor size (P=0.0319) and metastasis (P=0.0004), whereas no significant correlations were observed between NPTX1 expression and other factors, such as gender, age, α-fetoprotein (AFP), hepatitis B virus (HBV) DNA copies and differentiation (Table 1).