To test the co-occurrence of PTGS2-expressing thyroid tumor cells and M2-macrophages in human specimens, we assessed the expression levels of PTGS2 and the M2 marker CD163 in the trascriptomes of a series of 178 human thyroid tissues, publicly available on GEO, and including 58 normal thyroids, 72 PTCs, 17 PDTCs and 31 ATCs. This evidence concerns the gene PTGS2 and thyroid tumor.