POMC and adrenal gland hyperfunction: Biochemical testing indicated severe hypercortisolism: mean 24-hour UFC 322.7 μg/d (891 nmol/d) [ULN <50 μg/d (<138 nmol/d)], mean LNSC 5.73 ng/mL (15.8 nmol/L) [ULN <1.49 ng/mL (<4.1 nmol/L)], and mean morning ACTH <1.1 pg/mL (0.24 pmol/L) [normal range 7.2 to 63.3 pg/mL (1.6 to 13.9 pmol/L)].