Thedeceased group of acute AD patients showed a higher plasma IL-6 level than thesurvival patients (17.92±4.61 pg/mL vs.12.59±2.53 pg/mL, P<0.001) (Figure 1F), indicating that IL-6 could be a predictivebiomarker for mortality, and the cutoff value for the prediction of death shouldbe 18.36 pg/mL, with a sensitivity of 87.4% and a specificity of70.8%[16]. The gene discussed is IL6; the disease is Alzheimer disease.