VPA was found to significantly induce acetylation of p53 (K382) and IFNα-2b to significantly induce phosphorylation of STAT1 (Y701) and STAT3 (Y705) both in healthy donor and AML PBMCs (Figs. 5 and 6), validating the finding made by flow cytometry in the MOLM-13 cell line (Fig. 3). This evidence concerns the gene STAT1 and acute myeloid leukemia.