Additionally, mRNA expression of YWHAE, ARMC6, RAB11B, P4HB, SNRPA and ANP32A is down-regulated and CAPZB up-regulated by VPA in AML cell lines (Rucker et al. 2016), further supporting the existence of overlapping signaling pathways for IFNα and VPA. This evidence concerns the gene P4HB and acute myeloid leukemia.