APTX and spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 1: Ataxia with oculomotor apraxia-1 (AOA1) is caused by mutations in aprataxin (APTX), spinocerebellar ataxia with axonal neuropathy-1 (SCAN1) is derived from mutated Tyrosyl-DNA Phosphodiesterase 1 (TDP1).