miR-203 methylation and low expression are associated with metastasis in ccRCC. SNHG14 sponging miR-203 and elevating N-WASP as ceRNA promotes ccRCC migration and invasion. Overexpression of miR-203 inhibited migration, invasion, and induced apoptosis and cell cycle arrest. miR-203-HOTAIR interaction inhibited EMT and metastatic genes. This evidence concerns the gene WASL and nonpapillary renal cell carcinoma.