Comparisons of IL-2 induced pSTAT5 positive T-cells showed increased proportions in CD4+ T-cells from γc high as compared to γc low T1D patients (p = 0.004) (Figure 5D) and a similar tendency was seen for IL-15 (p = 0.068) (Supplementary Figure 4B, right graph). This evidence concerns the gene IL2 and type 1 diabetes mellitus.