ICAM1 and synovial sarcoma: These data suggest that functional and organic damage of media layer smooth cells in SS may be determined by a cellular infiltration of subendothelial space and the increased serum levels of adhesion molecules, such as ICAM-1 and VCAM-1, detected in SS patients may support that upregulation of these molecules on endothelial layer facilitates leukocyte infiltration within arterial wall with subsequent induction of atherosclerotic damage (38).