Stimulation of macrophages with 300 μM BzATP for 1 h following LPS treatment provoked IL-1β release significantly lower in SLE-S compared to SLE-NS (988.7 ± 103.6 vs. 1237 ± 70.39; p = 0.048) whereas no significant difference was found with HC (Figure 3C). This evidence concerns the gene IL1B and systemic lupus erythematosus.