NLRP3 and systemic lupus erythematosus: On the contrary, NLRP3 expression resulted significantly higher in PBMCs of patients than in controls (SLE vs. HC = 3.80 ± 0.46 vs. 1.99 ± 0.30; p = 0.018) also considering the two sub-categories separately (SLE-NS vs. HC = 3.846 ± 0.633 vs. 1.995 ± 0.302, p = 0.013; SLE-S vs. HC = 3.702 ± 0.552 vs. 1.995 ± 0.302, p = 0.036) (Figure 6B).